STUDIES ON THE BACTERIOPHAGES OF HEMOLYTIC STREPTOCOCCI

Studies on the Bacteriophages of Hemolytic Streptococci

The lysis of cell walls of hemolytic streptococci by a phage-associated lysin has been described. A method is presented for preparing the lysin from Group C streptococcal phage lysates. Following lysis almost all of the cell wall carbohydrate is recovered in solution. This material has the serological reactivity, physical-chemical properties, and values for nitrogen, rhamnose, and glucosamine s...

Studies on Bacteriophages of Hemolytic Streptococci

The host ranges of bacteriophages for group A, types 1, 6, 12, and 25 and group C streptococci have been determined. The findings indicate that the susceptibility to these phages is primarily a group-specific phenomenon, although it is modified by several factors such as the hyaluronic acid capsule, lysogeny, and possibly the presence of surface proteins. Phage antibody studies indicate that wh...

STUDIES ON BACTERIOPHAGES OF HEMOLYTIC STREPTOCOCCI I. FACTORS INFLUENCING THE INterACTION OF PHAGE AND SUSCEPTmLE

The bacteriophages of ~-hemolytic streptococci studied by Evans (1-4) were classified into several races or types. I t is clear from this early work that the phages demonstrated some degree of specificity for streptococcal groups. For instance, a bacteriophage which lysed almost all group C streptococci did not lyse group A streptococci. However, much of this work was done prior to the serologi...

Studies on Hemolytic Streptococci: II. Streptococcus pyogenes.

Studies upon Minute Hemolytic Streptococci

1. Minute beta hemolytic streptococci were found to occur from one-third to one-half as frequently in normal individuals as do ordinary beta hemolytic streptococci. 2. They were rarely isolated from the rhinopharynges of individuals suffering from chronic disease. 3. In acute respiratory tract infection other than that due to the ordinary beta hemolytic streptococcus the incidence of minute str...